Volume 3, Issue 1

Editorial

1. Article

   Prophylactic measures

   Ambrose Furey

   pp. 1-1 · DOI: 10.4103/0974-8490.79107 · 2011

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2. Article

   Anti-ulcerogenic and in vitro antioxidant activities of Lagenaria breviflora (LB) whole fruit ethanolic extract in laboratory animals

   S. A. Onasanwo, Neetu Singh, A. B. Saba, A. A. Oyagbemi, O. A. Oridupa, Gautam Palit

   pp. 2-8 · DOI: 10.4103/0974-8490.79108 · 2011

   The present study was undertaken to evaluate the anti-ulcer and antioxidant activities of the ethanol extract of Lagenaria breviflora (EELB) whole fruit in laboratory rats. The anti-ulcer property of the ethanolic extrac…

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3. Article

   In vitro antiproliferative activity of Annona reticulata roots on human cancer cell lines

   H. M. Suresh, B. Shivakumar, K. Hemalatha, S. S. Heroor, D. S. Hugar, K. R. S. Sambasiva Rao

   pp. 9-12 · DOI: 10.4103/0974-8490.79109 · 2011

   The phytochemical and pharmacological activities of Annona reticulata components suggest a wide range of clinical application in lieu of cancer chemotherapy. Ethanol and aqueous extracts of roots of Annona reticulata Lin…

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4. Article

   Hepatoprotective activity of Ocimum sanctum alcoholic leaf extract against paracetamol-induced liver damage in Albino rats

   Kingshuk Lahon, Swarnamoni Das

   pp. 13-18 · DOI: 10.4103/0974-8490.79110 · 2011

   There is a lack of reliable hepatoprotective drugs in modern medicine to prevent and treat drug-induced liver damage. Leaves of Sacred/Holy Basil, i.e. Green Tulsi (Ocimum sanctum), belonging to family Lamiaceae are used…

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5. Article

   Mining of simple sequence repeats in the Genome of Gentianaceae

   R. Sathishkumar, P. T. V. Lakshmi, A. Annamalai, V. Arunachalam

   pp. 19-29 · DOI: 10.4103/0974-8490.79111 · 2011

   Simple sequence repeats (SSRs) or short tandem repeats are short repeat motifs that show high level of length polymorphism due to insertion or deletion mutations of one or more repeat types. Here, we present the detectio…

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6. Article

   The study of aqueous extract of Ficus religiosa Linn. on cytokine TNF-α in type 2 diabetic rats

   H. Kirana, M. V. Jali, B. P. Srinivasan

   pp. 30-34 · DOI: 10.4103/0974-8490.79112 · 2011

   Chronic systemic inflammation is an early process in pathogenesis of type 2 diabetes. Hence the present study was aimed to investigate the effect of traditionally known plant Ficus religiosa on elevated glucose and infla…

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7. Article

   Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability

   Anil Singhal, H. Jain, Vipin Singhal, Edwin J. Elias, Ahmad Showkat

   pp. 35-39 · DOI: 10.4103/0974-8490.79113 · 2011

   The aim of the present study is to develop a polymer (Guar Gum)-based matrix tablet (using quercetin as a model drug) with sufficient mechanical strength, and promising in vitro mouth-to- colon release profile. By defini…

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8. Article

   Evaluation of acute toxicity and hepatoprotective activity of the methanolic extract of Dichrostachys cinerea (Wight and Arn.) leaves

   P. Suresh Babu, V. Krishna, K. R. Maruthi, K. Shankarmurthy, Ramesh K. Babu

   pp. 40-43 · DOI: 10.4103/0974-8490.79114 · 2011

   D. cinerea are the chief source of drug compounds that are active against various ailments such as jaundice, inflammations rheumatism, fever, asthma, body ache, chest problems, toothache, ulcers, wounds, eye diseases and…

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9. Article

   Partial in vitro and in vivo red scorpion venom neutralization activity of Andrographis paniculata

   Ranjana I. Brahmane, Swanand S. Pathak, Vikrant V. Wanmali, Kartik J. Salwe, S. John Premendran, Bhawna B. Shinde

   pp. 44-48 · DOI: 10.4103/0974-8490.79115 · 2011

   Red scorpion (Mesobuthus tamulus) is the most lethal among all poisonous species of scorpions. Envenoming by Mesobuthus tamulus is quite common along the western coast of India, without any established therapy. Andrograp…

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10. Article

    Standardization of some herbal antidiabetic drugs in polyherbal formulation

    Harinarayan Singh Chandel, A. K. Pathak, Mukul Tailang

    pp. 49-56 · DOI: 10.4103/0974-8490.79116 · 2011

    Ayurvedic formulations are used to treat a wide variety of diseases including diabetes mellitus Standardization of herbal formulation is essential in order to assess the quality of drugs. The present paper reports standa…

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11. Article

    Analgesic activity and acute toxicity study of Semecarpus anacardium stem bark extracts using mice

    G. M. Lingaraju, H. Joy Hoskeri, V. Krishna, P. Suresh Babu

    pp. 57-61 · DOI: 10.4103/0974-8490.79117 · 2011

    The analgesic activity of petroleum ether, chloroform and methanol extracts of Semecarpus anacardium was investigated by tail flicking and writhing method using acetyl salicylic acid as the standard reference. The stairc…

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12. Article

    Effect of methanolic extract of Lagenaria siceraria (Molina) Standley fruits on marble-burying behavior in mice: Implications for obsessive–compulsive disorder

    R. P. Prajapati, M. V. Kalaria, V. P. Karkare, S. K. Parmar, N. R. Sheth

    pp. 62-66 · DOI: 10.4103/0974-8490.79118 · 2011

    Obsessive–compulsive disorder (OCD) is the fourth most common mental disorder and is diagnosed nearly as often as asthma and diabetes mellitus. Over the last decade, the inhibition of burying of glass marbles by mice has…

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13. Article

    Antihyperglycemic effect of the alcoholic seed extract of Swietenia macrophylla on streptozotocin-diabetic rats

    Kalpana Kalaivanan, Kodukkur Viswanathan Pugalendi

    pp. 67-71 · DOI: 10.4103/0974-8490.79119 · 2011

    Streptozotocin (STZ) selectively destroys the pancreatic insulin secreting cells, leaving less active cells and resulting in a diabetic state. The present study was designed to investigate the antihyperglycemic effect of…

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14. Article

    Biomedical Research from Ideation to Publication

    Arun H. S. Kumar

    pp. 72-78 · 2011

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