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Evaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity

1, 2★, 1, 2, 2★ Corresponding author

  1. 1Department of Pharmacognosy, National College of Pharmacy
  2. 2Department of Microbiology, Kuvempu University, Shankarghatta, Shimoga, Karnataka, India

CORRESPONDENCE

B. Thippeswamy

Department of Microbiology, Kuvempu University, Shankarghatta, Shimoga, Karnataka, India

thippeswamyb205@gmail.com

Volume 7, Issue 1 · pp. 81-84 · 2014 · DOI: 10.4103/0974-8490.147213

ABSTRACT

To assess the anthelmintic acivity of Bacillus cereus and Bacillus pumilus metabolites. The successive solvent extractions with petroleum ether, ethyl acetate and methanol. The solvent extracts were tested for anthelmintic activity against Pheretima posthuma at 20 mg/ml concentration. The time of paralysis and time of death of the worms was determined for all the extracts. Albendazole was taken as a standard reference and sterile water as a control. All the sample extracts showed significant anthelmintic activity in paralyzing the worms comparable with that of the standard drug. The time of death exhibited by BP metabolites was close to the time exhibited by standard. The study indicates both bacteria Bacillus cereus and Bacillus pumilus have anthelmintic activity indicating potential metabolites in them.

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    Kumar, M. L. V., Thippeswamy, B., Kuppust, I. L., Naveenkumar, K. J., & Shivakumar, C. K. (2014). Evaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity. Pharmacognosy Research, 7(1), 81-84. https://doi.org/10.4103/0974-8490.147213

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    © 2014 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0