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Identification of Bioactive Ingredients of Traditional Medicinal Plants Psiadia arabica Jaub. Tamarix articulata, Terminalia arjuna and Rhazya stricta by GC-MS in Saudi Arabia

1, 2, 3, 4, 5, 6

  1. 1Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, SAUDI ARABIA., 2Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, SAUDI ARABIA., 3Production of Bio-products for Industrial Application Research Group, King Abdulaziz University, Jeddah, SAUDI ARABIA.
  2. 2Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, SAUDI ARABIA.
  3. 3Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, SAUDI ARABIA., 4Director of R and D Department, Opticon Hygiene Consulting, Oechsli 78807 Zurich, SWITZERLAND.
  4. 4Department of Hematology, Faculty of Medicine, King Abdulaziz University, Jeddah, SAUDI ARABIA.
  5. 5Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, SAUDI ARABIA., 7Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, EGYPT.
  6. 6Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, EGYPT.

CORRESPONDENCE

Said Salama Moselhy

Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, EGYPT.

moselhy6@hotmail.com

Received: 10-02-2024; Accepted: 04-04-2024.

Volume 16, Issue 3 · pp. 570-573 · 2024 · DOI: 10.5530/pres.16.3.67

ABSTRACT

Objectives: This study identified the main bioactive constituents extracted from a mixture containing four plant extracts. Four Saudi Traditional Medicinal plant extracts containing Psiadia arabica Jaub, Tamarix articulata, Terminalia arjuna and Rhazya stricta were identified using GC-Mass.Materials and Methods: The samples Psiadia arabica Jaub, Tamarix articulata, Terminalia arjuna and Rhazya stricta were collected from various regions of Saudi Arabia. The air-dried parts of each plant were powdered and soaked in methanol for 24 hr, except Psiadia arabica Jaub in chloroform. After that, it was obtaining the concentration plant extract through a rotary evaporator. The mixture of plant extracts was analyzed by GC-MS spectrometry.Results: The most abundant compounds identified including heneicosane (7.3%), tetradecane 4,11-dimethyl- (7.11%), Phytol (1.5%), dodecane, 2,6,10-trimethyl- (1.9%) and hexadecane (1.1%), while the lowest concentrations were observed for 10-methylnonadecane, n-hexadecane, tridecane, 2-methyl-, Naphthalene, 1,2,4a,5,6,8a-hexahydro-4,7-dimethyl-1-(1-methylethyl)- and Dodecane, 2,6,11-trimethyl-. One of the main constituents noticed in the combination of four plants was heneicosane, which exhibits a strong antimicrobial effect. In addition, phytol showed multiple effects, including anti-inflammatory, antimicrobial, ant nociceptive, anxiolytic, metabolism-modulating and immune-modulating.Conclusion: These functional molecules identified are known to have different biological activities as antioxidant, antimicrobial, anti-proliferative and antidiabetic. Further studies needed to investigate the mechanism of action through signaling pathway in vivo and in vitro study.

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    Kumosani, T. A., Alnefayee, A., Barbour, E., Qari, M., Ahmed, T., & Moselhy, S. S. (2024). Identification of Bioactive Ingredients of Traditional Medicinal Plants Psiadia arabica Jaub. Tamarix articulata, Terminalia arjuna and Rhazya stricta by GC-MS in Saudi Arabia. Pharmacognosy Research, 16(3), 570-573. https://doi.org/10.5530/pres.16.3.67

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    © 2024 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0