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Evaluation of the Chemical Composition and Oral Antimicrobial Activity of the Essential Oil from the Leaves of Pimenta pseudocaryophyllus (Gomes) Landrum

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  1. 1Department of Industrial Biotechnology, Universidade Positivo, Curitiba, Paraná 81280‑330, BRAZIL.

CORRESPONDENCE

Marilisa Carneiro Leão Gabardo

Department of Industrial Biotechnology, Universidade Positivo, Curitiba, Paraná 81280‑330, BRAZIL.

marilisagabardo@gmail.com

Volume 12, Issue 1 · pp. 65-70 · 2020 · DOI: 10.4103/pr.pr_83_19

ABSTRACT

Background: Pimenta pseudocaryophyllus is a native species from Brazil, whose leaves are used in the traditional culture as medicinal plants, being reported with antimicrobial and antifungal properties.Objectives: The aim of this study is to analyze and characterize the chemical composition of the essential oil (EO) extracted from the leaves of P. pseudocaryophyllus, as well as to evaluate its potential for antimicrobial activity against pathogenic bacteria inhabiting the human oral cavity.Materials and Methods: The extraction was performed by steam distillation and the chemical composition was analyzed using gas chromatography‑mass spectrometry (GC‑MS). The antimicrobial potential of the EO against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis was evaluated by agar well diffusion method. Different dilutions of the EO (10, 5, 2.5, 1.25, 0.625, 0.312, 0.156, 0.078, and 0.039%, v/v) were tested against the micro-organisms in disk diffusion tests to evaluate the minimum inhibitory concentration.Results: The extraction yielded 0.65% of EO in relation to fresh leaves of P. pseudocaryophyllus. GC‑MS analysis identified eugenol, eucalyptol, and limonene as the major compounds of its. The material showed antimicrobial activity, especially against E. faecalis, with moderate activity against S. aureus, both at concentrations from 1.25% to 10%.Conclusion: The results suggested that this EO presents potential of activity against the oral micro-organisms here evaluated.

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    Maranho, L. T., Rosas, E. C., Costa, T. A., Ribas, J. L. C., Baratto‑Filho, F., & Gabardo, M. C. L. (2020). Evaluation of the Chemical Composition and Oral Antimicrobial Activity of the Essential Oil from the Leaves of Pimenta pseudocaryophyllus (Gomes) Landrum. Pharmacognosy Research, 12(1), 65-70. https://doi.org/10.4103/pr.pr_83_19

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    © 2020 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0