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In vitro Screening for Antioxidant and Antimicrobial Properties of Three Lebanese Medicinal Plants Crude Extracts

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  1. 1AZM Centre for Research in Biotechnology and Its Applications, Laboratory of Applied Biotechnology for Biomolecules, Biotherapy and Bioprocess, Lebanese University, Tripoli, LEBANON.

CORRESPONDENCE

Hoda Elbitar

AZM Centre for Research in Biotechnology and Its Applications, Laboratory of Applied Biotechnology for Biomolecules, Biotherapy and Bioprocess, Lebanese University, Tripoli, LEBANON.

elbitarhoda@yahoo.fr

Volume 11, Issue 2 · pp. 127-133 · 2019 · DOI: 10.4103/pr.pr_171_18

ABSTRACT

Background: Despite its small geographic area, Lebanon is characterized by a natural wealth in medicinal plants. Lebanese flora has about 2600 species, where >100 are endemic and are used in traditional medicine for their therapeutic effects.Objective: To evaluate the antioxidant and antimicrobial activities of dichloromethane, methanol, and aqueous crude extracts of three Lebanese medicinal plants: Geranium robertianum, Asphodelus microcarpus, and Alcea setosa.Materials and Methods: The antioxidant activity of different crude extracts was determined using the free radical, 1,1‑diphenyl‑2‑picrylhydrazyl. Antimicrobial activity was evaluated in a plate‑hole diffusion assay against two Gram‑negative (Pseudomonas aeruginosa and Escherichia coli) bacterial strains, one Gram‑positive (Staphylococcus aureus) bacterial strain, and a fungal strain (Candida albicans).Results: Methanol and aqueous extracts of G. robertianum possessed high scavenging activity (Radical scavenging activity ( RSA) >85%) at 0.3 mg/mL followed by the extracts of A. microcarpus which showed a moderate activity. G. robertianum extracts exhibited good inhibition diameters against S. aureus growth.Conclusion: Obtained results give an overall view on the bioactivities of three Lebanese medicinal plants crude extracts.

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    Alhage, J., & Elbitar, H. (2019). In vitro Screening for Antioxidant and Antimicrobial Properties of Three Lebanese Medicinal Plants Crude Extracts. Pharmacognosy Research, 11(2), 127-133. https://doi.org/10.4103/pr.pr_171_18

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    © 2019 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0